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Correlation between In Vitro Susceptibility of Scedosporium apiospermum to Voriconazole and In Vivo Outcome of Scedosporiosis in Guinea Pigs

We have evaluated the efficacy of voriconazole (VRC) in a systemic infection by Scedosporium apiospermum in immunodepressed guinea pigs. Animals were infected with two strains; one required a VRC MIC of 0.5 to 1 μg/ml, common for this fungus, and the other required a high MIC (8 μg/ml), unusual in t...

詳細記述

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書誌詳細
主要な著者: Capilla, Javier, Guarro, Josep
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC521912/
https://ncbi.nlm.nih.gov/pubmed/15388467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.4009-4011.2004
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