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Efficacy of Voriconazole in a Guinea Pig Model of Disseminated Invasive Aspergillosis

Voriconazole (VRC) was evaluated in an immunosuppressed-guinea pig model of invasive aspergillosis. VRC was more effective than amphotericin B or similar doses of itraconazole in the clearance of Aspergillus from tissues. VRC treatment regimens improved survival and significantly reduced tissue colo...

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Bibliographic Details
Main Authors: Kirkpatrick, William R., McAtee, Robert K., Fothergill, Annette W., Rinaldi, Michael G., Patterson, Thomas F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90166/
https://ncbi.nlm.nih.gov/pubmed/10991875
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