A classical PKA inhibitor increases the oncolytic effect of M1 virus via activation of exchange protein directly activated by cAMP 1

Oncolytic virotherapy is an emerging and promising treatment modality that uses replicating viruses as selective antitumor agents. Here, we report that a classical protein kinase A (PKA) inhibitor, H89, synergizes with oncolytic virus M1 in various cancer cells through activation of Epac1 (exchange...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Kai, Liang, Jiankai, Lin, Yuan, Zhang, Haipeng, Xiao, Xiao, Tan, Yaqian, Cai, Jing, Zhu, Wenbo, Xing, Fan, Hu, Jun, Yan, Guangmei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217030/
https://ncbi.nlm.nih.gov/pubmed/27374176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10305
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados