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Noradrenaline up‐regulates volume‐regulated chloride current by PKA‐independent cAMP/exchange protein activated by cAMP pathway in human atrial myocytes

BACKGROUND AND PURPOSE: Adrenergic regulation of cell volume‐regulated chloride current (I(Cl.vol)) is species‐dependent. The present study investigates the mechanism underlying adrenergic regulation of I(Cl.vol) in human atrial myocytes. EXPERIMENTAL APPROACH: Conventional whole‐cell patch voltage‐...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Xiao, Guo‐Sheng, Zhang, Yan‐Hui, Wang, Yan, Sun, Hai‐Ying, Baumgarten, Clive M, Li, Gui‐Rong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057899/
https://ncbi.nlm.nih.gov/pubmed/29900525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14392
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