Deficiency of the IRE1α-Autophagy Axis Enhances the Antitumor Effects of the Oncolytic Virus M1

Oncolytic virotherapy is an emerging treatment modality that uses replication-competent viruses to destroy cancer cells. M1 is a naturally occurring alphavirus (Togaviridae) which shows potent oncolytic activities against many cancers. Accumulation of unfolded proteins during virus replication leads...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Kai, Hu, Cheng, Xing, Fan, Gao, Mingshi, Liang, Jiankai, Xiao, Xiao, Cai, Jing, Tan, Yaqian, Hu, Jun, Zhu, Wenbo, Yin, Wei, Li, Yuan, Chen, Wenli, Lu, Bingzheng, Mai, Jialuo, Qiu, Pengxin, Su, Xingwen, Yan, Guangmei, Zhang, Haipeng, Lin, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827398/
https://ncbi.nlm.nih.gov/pubmed/29263275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01331-17
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