EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling

Cancer cells prefer glycolysis for energy metabolism, even when there is sufficient oxygen to make it unnecessary. This is called the Warburg effect, and it promotes tumorigenesis and malignant progression. In this study, we demonstrated that EZH2, a multifaceted oncogenic protein involved in tumor...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Pang, Bo, Zheng, Xiang-Rong, Tian, Jing-xia, Gao, Tai-hong, Gu, Guang-yan, Zhang, Rui, Fu, Yi-Bing, Pang, Qi, Li, Xin-Gang, Liu, Qian
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216711/
https://ncbi.nlm.nih.gov/pubmed/27259264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9761
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