EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling

Cancer cells prefer glycolysis for energy metabolism, even when there is sufficient oxygen to make it unnecessary. This is called the Warburg effect, and it promotes tumorigenesis and malignant progression. In this study, we demonstrated that EZH2, a multifaceted oncogenic protein involved in tumor...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pang, Bo, Zheng, Xiang-Rong, Tian, Jing-xia, Gao, Tai-hong, Gu, Guang-yan, Zhang, Rui, Fu, Yi-Bing, Pang, Qi, Li, Xin-Gang, Liu, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216711/
https://ncbi.nlm.nih.gov/pubmed/27259264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9761
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