EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling

Cancer cells prefer glycolysis for energy metabolism, even when there is sufficient oxygen to make it unnecessary. This is called the Warburg effect, and it promotes tumorigenesis and malignant progression. In this study, we demonstrated that EZH2, a multifaceted oncogenic protein involved in tumor...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Pang, Bo, Zheng, Xiang-Rong, Tian, Jing-xia, Gao, Tai-hong, Gu, Guang-yan, Zhang, Rui, Fu, Yi-Bing, Pang, Qi, Li, Xin-Gang, Liu, Qian
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216711/
https://ncbi.nlm.nih.gov/pubmed/27259264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9761
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