Inhibition of EZH2 primes the cardiac gene activation via removal of epigenetic repression during human direct cardiac reprogramming

Cardiovascular disease, until now, is still the leading cause of death in the United States. Due to the limited regenerative capacity of adult hearts, the damage caused by heart injury cannot be reversed and eventually progress into heart failure. In need of cardiovascular disease treatment, many th...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res
Main Authors: Tang, Yawen, Zhao, Lianzhong, Yu, Xufen, Zhang, Jianyi, Qian, Li, Jin, Jian, Lu, Rui, Zhou, Yang
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238038/
https://ncbi.nlm.nih.gov/pubmed/34087994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2021.102365
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