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DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining

In human cells DNA double strand breaks (DSBs) can be repaired by the non-homologous end-joining (NHEJ) pathway. In a background of NHEJ deficiency, DSBs with mismatched ends can be joined by an error-prone mechanism involving joining between regions of nucleotide microhomology. The majority of join...

詳細記述

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書誌詳細
主要な著者: Bentley, Johanne, Diggle, Christine P., Harnden, Patricia, Knowles, Margaret A., Kiltie, Anne E.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC521655/
https://ncbi.nlm.nih.gov/pubmed/15466592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh842
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