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DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining
In human cells DNA double strand breaks (DSBs) can be repaired by the non-homologous end-joining (NHEJ) pathway. In a background of NHEJ deficiency, DSBs with mismatched ends can be joined by an error-prone mechanism involving joining between regions of nucleotide microhomology. The majority of join...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521655/ https://ncbi.nlm.nih.gov/pubmed/15466592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh842 |
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