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Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions
Mitochondrial DNA (mtDNA) deletions are associated with various mitochondrial disorders. The deletions identified in humans are flanked by short, directly repeated mitochondrial DNA sequences; however, the mechanism of such DNA rearrangements has yet to be elucidated. In contrast to nuclear DNA (nDN...
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| Опубликовано в: : | Mol Biol Cell |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713127/ https://ncbi.nlm.nih.gov/pubmed/26609070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-05-0260 |
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