Increased proteasome activity determines human embryonic stem cell identity

Embryonic stem cells are able to replicate continuously in the absence of senescence and, therefore, are immortal in culture(1,2). While genome stability is central for survival of stem cells; proteome stability may play an equally important role in stem cell identity and function. Additionally, wit...

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Publicat a:Nature
Autors principals: Vilchez, David, Boyer, Leah, Morantte, Ianessa, Lutz, Margaret, Merkwirth, Carsten, Joyce, Derek, Spencer, Brian, Page, Lesley, Masliah, Eliezer, Berggren, W. Travis, Gage, Fred H., Dillin, Andrew
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215918/
https://ncbi.nlm.nih.gov/pubmed/22972301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11468
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