FOXO4 is necessary for neural differentiation of human embryonic stem cells

Proteostasis is critical for maintaining cell function and proteome stability may play an important role in human embryonic stem cell (hESC) immortality. Notably, hESC populations exhibit a high assembly of active proteasomes, a key node of the proteostasis network. FOXO4, an insulin/IGF-1 responsiv...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Vilchez, David, Boyer, Leah, Lutz, Margaret, Merkwirth, Carsten, Morantte, Ianessa, Tse, Chris, Spencer, Brian, Page, Lesley, Masliah, Eliezer, Berggren, William Travis, Gage, Fred H., Dillin, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864013/
https://ncbi.nlm.nih.gov/pubmed/23551888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12067
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