Increased proteasome activity determines human embryonic stem cell identity

Embryonic stem cells are able to replicate continuously in the absence of senescence and, therefore, are immortal in culture(1,2). While genome stability is central for survival of stem cells; proteome stability may play an equally important role in stem cell identity and function. Additionally, wit...

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Publicado no:Nature
Main Authors: Vilchez, David, Boyer, Leah, Morantte, Ianessa, Lutz, Margaret, Merkwirth, Carsten, Joyce, Derek, Spencer, Brian, Page, Lesley, Masliah, Eliezer, Berggren, W. Travis, Gage, Fred H., Dillin, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215918/
https://ncbi.nlm.nih.gov/pubmed/22972301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11468
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