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The Metalloprotease Meprin β Is an Alternative β-Secretase of APP
The membrane bound metalloprotease meprin β is important for collagen fibril assembly in connective tissue formation and for the detachment of the intestinal mucus layer for proper barrier function. Recent proteomic studies revealed dozens of putative new substrates of meprin β, including the amyloi...
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Publicado no: | Front Mol Neurosci |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5215381/ https://ncbi.nlm.nih.gov/pubmed/28105004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00159 |
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