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The Metalloprotease Meprin β Is an Alternative β-Secretase of APP

The membrane bound metalloprotease meprin β is important for collagen fibril assembly in connective tissue formation and for the detachment of the intestinal mucus layer for proper barrier function. Recent proteomic studies revealed dozens of putative new substrates of meprin β, including the amyloi...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Becker-Pauly, Christoph, Pietrzik, Claus U.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215381/
https://ncbi.nlm.nih.gov/pubmed/28105004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00159
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