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Altered antigen receptor signaling in anergic T cells from self-tolerant T-cell receptor beta-chain transgenic mice.

T-cell tolerance to the minor lymphocyte-stimulating antigen Mls-1a in a T-cell receptor (TcR) V beta 8.1 transgenic line of mice is maintained by both clonal deletion and clonal anergy. Approximately 20-50% of peripheral CD4+ (but not CD8+) T cells isolated from these mice are anergic and fail to p...

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Bibliografische gegevens
Hoofdauteurs: Blackman, M A, Finkel, T H, Kappler, J, Cambier, J, Marrack, P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1991
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC52152/
https://ncbi.nlm.nih.gov/pubmed/1907374
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