A method for production of antibodies to human T-cell receptor beta-chain variable regions.

Mouse T-cell hybridomas bearing human V beta elements were produced by transfection of human/mouse hybrid T-cell receptor beta-chain genes into a mouse T-cell hybridoma lacking an endogenous beta-chain gene. These hybridomas were entirely mouse in origin except for the human V beta region. These cel...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Choi, Y W, Kotzin, B, Lafferty, J, White, J, Pigeon, M, Kubo, R, Kappler, J, Marrack, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656442/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.19.8357
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