A method for production of antibodies to human T-cell receptor beta-chain variable regions.

Mouse T-cell hybridomas bearing human V beta elements were produced by transfection of human/mouse hybrid T-cell receptor beta-chain genes into a mouse T-cell hybridoma lacking an endogenous beta-chain gene. These hybridomas were entirely mouse in origin except for the human V beta region. These cel...

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Main Authors: Choi, Y W, Kotzin, B, Lafferty, J, White, J, Pigeon, M, Kubo, R, Kappler, J, Marrack, P
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC52507/
https://ncbi.nlm.nih.gov/pubmed/1656442
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