A method for producing monoclonal antibodies to human T-cell-receptor beta-chain variable regions.

Study of the T-cell repertoire in humans has been hampered by the lack of monoclonal antibodies (mAbs) to the T-cell receptor (TCR) variable region (V) gene products. We describe a method for producing mAbs to the human TCR beta-chain V (V beta) gene products in which mice were immunized with a rat...

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Hauptverfasser: Callan, M F, Reyburn, H T, Bowness, P, Ottenhoff, T H, Engel, I, Klausner, R D, Bell, J I, McMichael, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC47795/
https://ncbi.nlm.nih.gov/pubmed/8248131
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