T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.

To study T cell tolerance, transgenic mice were generated that expressed the Mlsa-reactive T cell receptor (TCR) beta chain V beta 8.1 (cDNA) under the control of the H-2Kb promoter/immunoglobulin heavy chain enhancer on approximately 90% of peripheral T cells. In transgenic mice bearing Mlsa, thymo...

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Bibliografiska uppgifter
I publikationen:EMBO J
Huvudupphovsmän: Pircher, H, Mak, T W, Lang, R, Ballhausen, W, Rüedi, E, Hengartner, H, Zinkernagel, R M, Bürki, K
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400867/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2524380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03431.x
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