Profound alteration in an alpha beta T-cell antigen receptor repertoire due to polymorphism in the first complementarity-determining region of the beta chain.

Amino acid residues that are critical in maintaining the framework structure of immunoglobulin heavy- and light-chain variable (V) regions are strongly conserved in the V alpha and V beta proteins of the alpha beta T-cell antigen receptor (TCR alpha beta). Consequently, it has been proposed that TCR...

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Autori principali: Gahm, S J, Fowlkes, B J, Jameson, S C, Gascoigne, N R, Cotterman, M M, Kanagawa, O, Schwartz, R H, Matis, L A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC52909/
https://ncbi.nlm.nih.gov/pubmed/1835090
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