Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells

In autoimmune prone murine strains, sequential engagement of the B cell antigen receptor (BCR) on the cell surface and toll-like receptors (TLRs) in late endosomes is necessary and sufficient for secretion of autoantibodies. However, ubiquitous nucleoprotein self-antigens fail to elicit productive T...

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Detalhes bibliográficos
Main Authors: O'Neill, Shannon K., Veselits, Margaret L., Zhang, Miao, Labno, Christine, Cao, Yanxia, Finnegan, Alison, Uccellini, Melissa, Alegre, Maria-Luisa, Cambier, John C., Clark, Marcus R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662959/
https://ncbi.nlm.nih.gov/pubmed/19332776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812922106
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