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Regulation of Toll and Toll-like receptor signaling by the endocytic pathway

The Toll/TLR receptor family plays a central role in both vertebrate and insect immunity, driving the activation of humoral immunity in response to pathogens. In Drosophila, Toll is also responsible for directing the formation of the Dorsal/NFkappaB gradient specifying dorsoventral patterning of the...

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Autors principals: Lund, Viktor K, DeLotto, Robert
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136911/
https://ncbi.nlm.nih.gov/pubmed/21776409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.2.15378
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