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Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

Immune responses are initiated when molecules of microbial origin are sensed by the Toll-like receptors (TLRs). We now report the identification of essential molecular components for the trafficking of the lipopolysaccharide (LPS) receptor complex. LPS was endocytosed by a receptor-mediated mechanis...

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Detalhes bibliográficos
Main Authors: Husebye, Harald, Halaas, Øyvind, Stenmark, Harald, Tunheim, Gro, Sandanger, Øystein, Bogen, Bjarne, Brech, Andreas, Latz, Eicke, Espevik, Terje
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383569/
https://ncbi.nlm.nih.gov/pubmed/16467847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600991
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