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Endocytic pathway is required for Drosophila Toll innate immune signaling

The Toll signaling pathway is required for the innate immune response against fungi and Gram-positive bacteria in Drosophila. Here we show that the endosomal proteins Myopic (Mop) and Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) are required for the activation of the Toll signa...

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Hlavní autoři: Huang, Hon-Ren, Chen, Zhijian J., Kunes, Sam, Chang, Geen-Dong, Maniatis, Tom
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889516/
https://ncbi.nlm.nih.gov/pubmed/20404143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004031107
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