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Oxidized CaMKII promotes asthma through the activation of mast cells
Oxidation of calmodulin-dependent protein kinase II (ox-CaMKII) by ROS has been associated with asthma. However, the contribution of ox-CaMKII to the development of asthma remains to be fully characterized. Here, we tested the effect of ox-CaMKII on IgE-mediated mast cell activation in an allergen-i...
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| Publicado en: | JCI Insight |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5214090/ https://ncbi.nlm.nih.gov/pubmed/28097237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.90139 |
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