Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function

Integrins are transmembrane receptors composed of α and β subunits. Although most integrins contain β1, canonical activation mechanisms are based on studies of the platelet integrin, αIIbβ3. Its inactive conformation is characterized by the association of the αIIb transmembrane and cytosolic domain...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Lu, Zhenwei, Mathew, Sijo, Chen, Jiang, Hadziselimovic, Arina, Palamuttam, Riya, Hudson, Billy G, Fässler, Reinhard, Pozzi, Ambra, Sanders, Charles R, Zent, Roy
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2016
Soggetti:
Biochemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207772/
https://ncbi.nlm.nih.gov/pubmed/27929375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18633
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi