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Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function

Integrins are transmembrane receptors composed of α and β subunits. Although most integrins contain β1, canonical activation mechanisms are based on studies of the platelet integrin, αIIbβ3. Its inactive conformation is characterized by the association of the αIIb transmembrane and cytosolic domain...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:eLife
मुख्य लेखकों: Lu, Zhenwei, Mathew, Sijo, Chen, Jiang, Hadziselimovic, Arina, Palamuttam, Riya, Hudson, Billy G, Fässler, Reinhard, Pozzi, Ambra, Sanders, Charles R, Zent, Roy
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: eLife Sciences Publications, Ltd 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207772/
https://ncbi.nlm.nih.gov/pubmed/27929375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18633
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