Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function

Integrins are transmembrane receptors composed of α and β subunits. Although most integrins contain β1, canonical activation mechanisms are based on studies of the platelet integrin, αIIbβ3. Its inactive conformation is characterized by the association of the αIIb transmembrane and cytosolic domain...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Lu, Zhenwei, Mathew, Sijo, Chen, Jiang, Hadziselimovic, Arina, Palamuttam, Riya, Hudson, Billy G, Fässler, Reinhard, Pozzi, Ambra, Sanders, Charles R, Zent, Roy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Biochemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207772/
https://ncbi.nlm.nih.gov/pubmed/27929375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18633
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