The Stalk Domain of NKp30 Contributes to Ligand Binding and Signaling of a Preassembled NKp30-CD3ζ Complex

The natural cytotoxicity receptor (NCR) NKp30 (CD337) is a key player for NK cell immunosurveillance of infections and cancer. The molecular details of ligand recognition and its connection to CD3ζ signaling remain unsolved. Here, we show that the stalk domain ((129)KEHPQLGAGTVLLLR(143)) of NKp30 is...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Memmer, Stefanie, Weil, Sandra, Beyer, Steffen, Zöller, Tobias, Peters, Eike, Hartmann, Jessica, Steinle, Alexander, Koch, Joachim
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207244/
https://ncbi.nlm.nih.gov/pubmed/27754869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742981
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi