NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients

Despite effective targeted therapy acting on KIT and PDGFRA tyrosine kinases, gastrointestinal stromal tumors (GIST) escape treatment by acquiring mutations conveying resistance to imatinib mesylate (IM). Following the identification of NKp30-based immunosurveillance of GIST and the off-target effec...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncoimmunology
Prif Awduron: Rusakiewicz, Sylvie, Perier, Aurélie, Semeraro, Michaela, Pitt, Jonathan M., Pogge von Strandmann, Elke, Reiners, Katrin S., Aspeslagh, Sandrine, Pipéroglou, Christelle, Vély, Frédéric, Ivagnes, Alexandre, Jegou, Sarah, Halama, Niels, Chaigneau, Loic, Validire, Pierre, Christidis, Christos, Perniceni, Thierry, Landi, Bruno, Berger, Anne, Isambert, Nicolas, Domont, Julien, Bonvalot, Sylvie, Terrier, Philippe, Adam, Julien, Coindre, Jean-Michel, Emile, Jean-François, Poirier-Colame, Vichnou, Chaba, Kariman, Rocha, Benedita, Caignard, Anne, Toubert, Antoine, Enot, David, Koch, Joachim, Marabelle, Aurélien, Lambert, Marion, Caillat-Zucman, Sophie, Leyvraz, Serge, Auclair, Christian, Vivier, Eric, Eggermont, Alexander, Borg, Christophe, Blay, Jean-Yves, Le Cesne, Axel, Mir, Olivier, Zitvogel, Laurence
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283614/
https://ncbi.nlm.nih.gov/pubmed/28197361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1137418
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