NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients

Despite effective targeted therapy acting on KIT and PDGFRA tyrosine kinases, gastrointestinal stromal tumors (GIST) escape treatment by acquiring mutations conveying resistance to imatinib mesylate (IM). Following the identification of NKp30-based immunosurveillance of GIST and the off-target effec...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Rusakiewicz, Sylvie, Perier, Aurélie, Semeraro, Michaela, Pitt, Jonathan M., Pogge von Strandmann, Elke, Reiners, Katrin S., Aspeslagh, Sandrine, Pipéroglou, Christelle, Vély, Frédéric, Ivagnes, Alexandre, Jegou, Sarah, Halama, Niels, Chaigneau, Loic, Validire, Pierre, Christidis, Christos, Perniceni, Thierry, Landi, Bruno, Berger, Anne, Isambert, Nicolas, Domont, Julien, Bonvalot, Sylvie, Terrier, Philippe, Adam, Julien, Coindre, Jean-Michel, Emile, Jean-François, Poirier-Colame, Vichnou, Chaba, Kariman, Rocha, Benedita, Caignard, Anne, Toubert, Antoine, Enot, David, Koch, Joachim, Marabelle, Aurélien, Lambert, Marion, Caillat-Zucman, Sophie, Leyvraz, Serge, Auclair, Christian, Vivier, Eric, Eggermont, Alexander, Borg, Christophe, Blay, Jean-Yves, Le Cesne, Axel, Mir, Olivier, Zitvogel, Laurence
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2016
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283614/
https://ncbi.nlm.nih.gov/pubmed/28197361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1137418
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares