NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients

Despite effective targeted therapy acting on KIT and PDGFRA tyrosine kinases, gastrointestinal stromal tumors (GIST) escape treatment by acquiring mutations conveying resistance to imatinib mesylate (IM). Following the identification of NKp30-based immunosurveillance of GIST and the off-target effec...

詳細記述

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書誌詳細
出版年:Oncoimmunology
主要な著者: Rusakiewicz, Sylvie, Perier, Aurélie, Semeraro, Michaela, Pitt, Jonathan M., Pogge von Strandmann, Elke, Reiners, Katrin S., Aspeslagh, Sandrine, Pipéroglou, Christelle, Vély, Frédéric, Ivagnes, Alexandre, Jegou, Sarah, Halama, Niels, Chaigneau, Loic, Validire, Pierre, Christidis, Christos, Perniceni, Thierry, Landi, Bruno, Berger, Anne, Isambert, Nicolas, Domont, Julien, Bonvalot, Sylvie, Terrier, Philippe, Adam, Julien, Coindre, Jean-Michel, Emile, Jean-François, Poirier-Colame, Vichnou, Chaba, Kariman, Rocha, Benedita, Caignard, Anne, Toubert, Antoine, Enot, David, Koch, Joachim, Marabelle, Aurélien, Lambert, Marion, Caillat-Zucman, Sophie, Leyvraz, Serge, Auclair, Christian, Vivier, Eric, Eggermont, Alexander, Borg, Christophe, Blay, Jean-Yves, Le Cesne, Axel, Mir, Olivier, Zitvogel, Laurence
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2016
主題:
Original Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5283614/
https://ncbi.nlm.nih.gov/pubmed/28197361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1137418
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