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The Stalk Domain of NKp30 Contributes to Ligand Binding and Signaling of a Preassembled NKp30-CD3ζ Complex
The natural cytotoxicity receptor (NCR) NKp30 (CD337) is a key player for NK cell immunosurveillance of infections and cancer. The molecular details of ligand recognition and its connection to CD3ζ signaling remain unsolved. Here, we show that the stalk domain ((129)KEHPQLGAGTVLLLR(143)) of NKp30 is...
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| 發表在: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5207244/ https://ncbi.nlm.nih.gov/pubmed/27754869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742981 |
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