Crystal Structures of the Nuclear Receptor, Liver Receptor Homolog 1, Bound to Synthetic Agonists

Liver receptor homolog 1 (NR5A2, LRH-1) is an orphan nuclear hormone receptor that regulates diverse biological processes, including metabolism, proliferation, and the resolution of endoplasmic reticulum stress. Although preclinical and cellular studies demonstrate that LRH-1 has great potential as...

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Vydáno v:J Biol Chem
Hlavní autoři: Mays, Suzanne G., Okafor, C. Denise, Whitby, Richard J., Goswami, Devrishi, Stec, Józef, Flynn, Autumn R., Dugan, Michael C., Jui, Nathan T., Griffin, Patrick R., Ortlund, Eric A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207232/
https://ncbi.nlm.nih.gov/pubmed/27694446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753541
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