Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes

Fibrosis, driven by inflammation, marks the transition from benign to progressive stages of chronic liver diseases. Although inflammation promotes fibrogenesis, it is not known whether other events, such as hepatocyte death, are required for the development of fibrosis. Interferon regulatory factor...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Iracheta-Vellve, Arvin, Petrasek, Jan, Gyongyosi, Benedek, Satishchandran, Abhishek, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Calenda, Charles D., Kurt-Jones, Evelyn A., Fitzgerald, Katherine A., Szabo, Gyongyi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207187/
https://ncbi.nlm.nih.gov/pubmed/27810900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.736991
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