Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes

Fibrosis, driven by inflammation, marks the transition from benign to progressive stages of chronic liver diseases. Although inflammation promotes fibrogenesis, it is not known whether other events, such as hepatocyte death, are required for the development of fibrosis. Interferon regulatory factor...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Iracheta-Vellve, Arvin, Petrasek, Jan, Gyongyosi, Benedek, Satishchandran, Abhishek, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Calenda, Charles D., Kurt-Jones, Evelyn A., Fitzgerald, Katherine A., Szabo, Gyongyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207187/
https://ncbi.nlm.nih.gov/pubmed/27810900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.736991
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