Endoplasmic Reticulum Stress-induced Hepatocellular Death Pathways Mediate Liver Injury and Fibrosis via Stimulator of Interferon Genes

Fibrosis, driven by inflammation, marks the transition from benign to progressive stages of chronic liver diseases. Although inflammation promotes fibrogenesis, it is not known whether other events, such as hepatocyte death, are required for the development of fibrosis. Interferon regulatory factor...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Iracheta-Vellve, Arvin, Petrasek, Jan, Gyongyosi, Benedek, Satishchandran, Abhishek, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Calenda, Charles D., Kurt-Jones, Evelyn A., Fitzgerald, Katherine A., Szabo, Gyongyi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207187/
https://ncbi.nlm.nih.gov/pubmed/27810900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.736991
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