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β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4

The chemokine receptor CXCR4 and its chemokine ligand CXCL12 mediate directed cell migration during organogenesis, immune responses, and metastatic disease. However, the mechanisms governing CXCL12/CXCR4-dependent chemotaxis remain poorly understood. Here, we show that the β-arrestin1·signal-transdu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Alekhina, Olga, Marchese, Adriano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207078/
https://ncbi.nlm.nih.gov/pubmed/27789711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.757138
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