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The Endosomal Sorting Complex Required for Transport Pathway Mediates Chemokine Receptor CXCR4-promoted Lysosomal Degradation of the Mammalian Target of Rapamycin Antagonist DEPTOR

G protein-coupled receptor (GPCR) signaling mediates many cellular functions, including cell survival, proliferation, and cell motility. Many of these processes are mediated by GPCR-promoted activation of Akt signaling by mammalian target of rapamycin complex 2 (mTORC2) and the phosphatidylinositol...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Verma, Rita, Marchese, Adriano
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358107/
https://ncbi.nlm.nih.gov/pubmed/25605718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.606699
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