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The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein–coupled receptor CXCR4

G protein–coupled receptor (GPCR) sorting into the degradative pathway is important for limiting the duration and magnitude of signaling. Agonist activation of the GPCR CXCR4 induces its rapid ubiquitination and sorting to lysosomes via the endosomal sorting complex required for transport (ESCRT) pa...

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Autors principals: Holleman, Justine, Marchese, Adriano
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055268/
https://ncbi.nlm.nih.gov/pubmed/24790097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-10-0612
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