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The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein–coupled receptor CXCR4

G protein–coupled receptor (GPCR) sorting into the degradative pathway is important for limiting the duration and magnitude of signaling. Agonist activation of the GPCR CXCR4 induces its rapid ubiquitination and sorting to lysosomes via the endosomal sorting complex required for transport (ESCRT) pa...

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Auteurs principaux: Holleman, Justine, Marchese, Adriano
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055268/
https://ncbi.nlm.nih.gov/pubmed/24790097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-10-0612
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