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The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein–coupled receptor CXCR4
G protein–coupled receptor (GPCR) sorting into the degradative pathway is important for limiting the duration and magnitude of signaling. Agonist activation of the GPCR CXCR4 induces its rapid ubiquitination and sorting to lysosomes via the endosomal sorting complex required for transport (ESCRT) pa...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055268/ https://ncbi.nlm.nih.gov/pubmed/24790097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-10-0612 |
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