Signal-Transducing Adaptor Molecules STAM1 and STAM2 Are Required for T-Cell Development and Survival

We previously reported that the STAM family members STAM1 and STAM2 are phosphorylated on tyrosine upon stimulation with cytokines through the γc-Jak3 signaling pathway, which is essential for T-cell development. Mice with targeted mutations in either STAM1 or STAM2 show no abnormality in T-cell dev...

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Détails bibliographiques
Auteurs principaux: Yamada, Mitsuhiro, Ishii, Naoto, Asao, Hironobu, Murata, Kazuko, Kanazawa, Chieko, Sasaki, Hidetada, Sugamura, Kazuo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC139881/
https://ncbi.nlm.nih.gov/pubmed/12446783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8648-8658.2002
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