β-Arrestin1 and β-Arrestin2 Are Required to Support the Activity of the CXCL12/HMGB1 Heterocomplex on CXCR4

The chemokine receptor CXCR4 plays a fundamental role in homeostasis and pathology by orchestrating recruitment and positioning of immune cells, under the guidance of a CXCL12 gradient. The ability of chemokines to form heterocomplexes, enhancing their function, represents an additional level of reg...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: D’Agostino, Gianluca, Artinger, Marc, Locati, Massimo, Perez, Laurent, Legler, Daniel F., Bianchi, Marco E., Rüegg, Curzio, Thelen, Marcus, Marchese, Adriano, Rocchi, Marco B. L., Cecchinato, Valentina, Uguccioni, Mariagrazia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533569/
https://ncbi.nlm.nih.gov/pubmed/33072091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.550824
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