ACKR4 Recruits GRK3 Prior to β-Arrestins but Can Scavenge Chemokines in the Absence of β-Arrestins

Chemokines are essential for guiding cell migration. Atypical chemokine receptors (ACKRs) contribute to the cell migration process by binding, internalizing and degrading local chemokines, which enables the formation of confined gradients. ACKRs are heptahelical membrane spanning molecules structura...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Matti, Christoph, Salnikov, Angela, Artinger, Marc, D'Agostino, Gianluca, Kindinger, Ilona, Uguccioni, Mariagrazia, Thelen, Marcus, Legler, Daniel F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188906/
https://ncbi.nlm.nih.gov/pubmed/32391018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00720
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