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Conservation of coevolving protein interfaces bridges prokaryote–eukaryote homologies in the twilight zone
Protein–protein interactions are fundamental for the proper functioning of the cell. As a result, protein interaction surfaces are subject to strong evolutionary constraints. Recent developments have shown that residue coevolution provides accurate predictions of heterodimeric protein interfaces fro...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206536/ https://ncbi.nlm.nih.gov/pubmed/27965389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611861114 |
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