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Conservation of coevolving protein interfaces bridges prokaryote–eukaryote homologies in the twilight zone
Protein–protein interactions are fundamental for the proper functioning of the cell. As a result, protein interaction surfaces are subject to strong evolutionary constraints. Recent developments have shown that residue coevolution provides accurate predictions of heterodimeric protein interfaces fro...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206536/ https://ncbi.nlm.nih.gov/pubmed/27965389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611861114 |
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