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A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes

Epidermal growth factor receptor (EGFr) is a key mediator of cell communication during animal development and homeostasis. In Drosophila, the signaling event is commonly regulated by the polytopic membrane protein Rhomboid (RHO), which mediates the proteolytic activation of EGFr ligands, allowing th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gallio, Marco, Sturgill, Gwen, Rather, Philip, Kylsten, Per
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC129423/
https://ncbi.nlm.nih.gov/pubmed/12221285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192138799
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