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A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes

Epidermal growth factor receptor (EGFr) is a key mediator of cell communication during animal development and homeostasis. In Drosophila, the signaling event is commonly regulated by the polytopic membrane protein Rhomboid (RHO), which mediates the proteolytic activation of EGFr ligands, allowing th...

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Detalhes bibliográficos
Main Authors: Gallio, Marco, Sturgill, Gwen, Rather, Philip, Kylsten, Per
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129423/
https://ncbi.nlm.nih.gov/pubmed/12221285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192138799
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