Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription.
Investigations of the actions and interactions of the immunophilin ligands FK506, cyclosporin A (CsA), rapamycin, and 506BD suggest that complexes of FK506 with an FK506-binding protein or of CsA with a cyclophilin (CsA-binding protein) inhibit the T-cell receptor-mediated signal transduction that r...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1991
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52056/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1712484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.14.6229 |
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