A beta subunit mutation disrupting the catalytic function of Escherichia coli RNA polymerase.
The substitution of the evolutionarily conserved Glu-813 for lysine in the beta subunit of RNA polymerase (RNAP) causes a partial loss of function in the assembled RNAP. In the presence of the four ribonucleoside triphosphates, the mutant RNAP displayed a decreased frequency of promoter clearance an...
שמור ב:
| הוצא לאור ב: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
1991
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52013/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2068078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.14.6018 |
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